Olinone

Modify Date: 2025-08-24 23:56:47

Olinone structure	Common Name	Olinone
	CAS Number	1770789-37-1	Molecular Weight	299.37
	Density	1.3±0.1 g/cm3	Boiling Point	675.6±55.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₁N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	362.4±31.5 °C

Use of Olinone

Olinone is a selective BRD4 BrD1 inhibitor[1]. Olinone accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation[2].

Name	N-[4-(1-Oxo-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)butyl]acetamide
Synonym	More Synonyms

Description	Olinone is a selective BRD4 BrD1 inhibitor[1]. Olinone accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation[2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
References	[1]. Rodríguez Y, et al. In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4. Proteins. 2020 Mar;88(3):414-430. [2]. Gacias M, et al. Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression. Chem Biol. 2014 Jul 17;21(7):841-854.

Description

Olinone is a selective BRD4 BrD1 inhibitor[1]. Olinone accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation[2].

Related Catalog

Research Areas >> Neurological Disease

Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

References

[1]. Rodríguez Y, et al. In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4. Proteins. 2020 Mar;88(3):414-430.

[2]. Gacias M, et al. Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression. Chem Biol. 2014 Jul 17;21(7):841-854.

Density	1.3±0.1 g/cm3
Boiling Point	675.6±55.0 °C at 760 mmHg
Molecular Formula	C₁₇H₂₁N₃O₂
Molecular Weight	299.37
Flash Point	362.4±31.5 °C
Exact Mass	299.163391
LogP	0.62
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.643
InChIKey	RYVLOOXFFIFQEN-UHFFFAOYSA-N
SMILES	CC(=O)NCCCCn1c2c(c3ccccc31)C(=O)NCC2
Storage condition	-20°C

Hazard Codes	T+

N-[4-(1-Oxo-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)butyl]acetamide

Acetamide, N-[4-(1,2,3,4-tetrahydro-1-oxo-5H-pyrido[4,3-b]indol-5-yl)butyl]-

MFCD28976195

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Olinone
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Olinone
Price: $450.0/25mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Olinone
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: CCT244747
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.