4-Methylumbelliferyl butyrate

Modify Date: 2025-08-21 13:24:11

4-Methylumbelliferyl butyrate structure	Common Name	4-Methylumbelliferyl butyrate
	CAS Number	17695-46-4	Molecular Weight	246.25900
	Density	1.197 g/cm3	Boiling Point	393.4ºC at 760 mmHg
	Molecular Formula	C₁₄H₁₄O₄	Melting Point	90-92ºC(lit.)
	MSDS	Chinese USA	Flash Point	199.8ºC

Use of 4-Methylumbelliferyl butyrate

4-Methylumbelliferyl butyrate (4-MUB) is a coumarin-based fluorogenic substrate used for the identification of M. catarrhalis C4- esterase. 4-Methylumbelliferyl butyrate can converse to the blue-emissive 4-methylumbelliferone (4-MU; HY-N0187)[1].

Name	4-Methylumbelliferyl butyrate
Synonym	More Synonyms

Description	4-Methylumbelliferyl butyrate (4-MUB) is a coumarin-based fluorogenic substrate used for the identification of M. catarrhalis C4- esterase. 4-Methylumbelliferyl butyrate can converse to the blue-emissive 4-methylumbelliferone (4-MU; HY-N0187)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Uisung Lee, et al. Selective Butyrate Esterase Probe for the Rapid Colorimetric and Fluorogenic Identification of Moraxella catarrhalis. Anal Chem. 2020 Dec 15;92(24):16051-16057.

Density	1.197 g/cm3
Boiling Point	393.4ºC at 760 mmHg
Melting Point	90-92ºC(lit.)
Molecular Formula	C₁₄H₁₄O₄
Molecular Weight	246.25900
Flash Point	199.8ºC
Exact Mass	246.08900
PSA	56.51000
LogP	2.80690
Vapour Pressure	2.13E-06mmHg at 25°C
Index of Refraction	1.545
InChIKey	WKPUJZVCZXWKCK-UHFFFAOYSA-N
SMILES	CCCC(=O)Oc1ccc2c(C)cc(=O)oc2c1
Storage condition	-20°C

4-Methylumbelliferyl butyrate MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	T+
Risk Phrases	R26/27/28
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
HS Code	2932209090

4-Methylumbelli...

CAS#:90-33-5

Butyryl chloride

CAS#:141-75-3

~94%

4-Methylumbelli...

CAS#:17695-46-4

Literature: Instytut Chemii Organicznej, Polska Akademia Nauk Patent: WO2009/67031 A1, 2009 ; Location in patent: Page/Page column 14 ;

Butanoic anhydride

CAS#:106-31-0

4-Methylumbelli...

CAS#:90-33-5

4-Methylumbelli...

CAS#:17695-46-4

Literature: Journal of the American Chemical Society, , vol. 62, p. 1441,1443

Precursor 3
CAS#:90-33-5 4-Methylumbelli... CAS#:141-75-3 Butyryl chloride CAS#:106-31-0 Butanoic anhydride
DownStream 4
CAS#:90-33-5 4-Methylumbelli... CAS#:107-92-6 Butyric Acid CAS#:90104-80-6 2H-1-Benzopyran... CAS#:35031-57-3 2-4-dimethylbut...

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Rapid identification of Branhamella catarrhalis with 4-methylumbelliferyl butyrate.

J. Clin. Microbiol. 26 , 1227, (1988)

Branhamella catarrhalis can be distinguished from Neisseria spp. by the presence of butyrate esterase. This enzyme can be rapidly detected when 4-methylumbelliferyl butyrate is used as the substrate. ...

Characterization of an acidic cold-adapted cutinase from Thielavia terrestris and its application in flavor ester synthesis.

Food Chem. 188 , 439-45, (2015)

An acidic cutinase (TtcutB) from Thielavia terrestris CAU709 was purified to apparent homogeneity with 983 Um g(-1) specific activity. The molecular mass of the enzyme was estimated to be 27.3 and 27....

Fluorescence spectroscopic analysis of the structure and dynamics of Bacillus subtilis lipase A governing its activity profile under alkaline conditions.

Eur. Biophys. J. 44 , 655-65, (2015)

Because of their vast diversity of substrate specificity and reaction conditions, lipases are versatile materials for biocatalysis. Lipase A from Bacillus subtilis (BSLA) is the smallest lipase yet di...

(4-methyl-2-oxochromen-7-yl) butanoate

MFCD00038087

EINECS 241-694-7