Tetramethylrhodamine-6-maleimide

Modify Date: 2024-01-13 17:38:41

Tetramethylrhodamine-6-maleimide Structure
Tetramethylrhodamine-6-maleimide structure
Common Name Tetramethylrhodamine-6-maleimide
CAS Number 174568-68-4 Molecular Weight 481.49900
Density N/A Boiling Point N/A
Molecular Formula C28H23N3O5 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Tetramethylrhodamine-6-maleimide


Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time[1][2].

 Names

Name 2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-(2,5-dioxopyrrol-1-yl)benzoate
Synonym More Synonyms

 Tetramethylrhodamine-6-maleimide Biological Activity

Description Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time[1][2].
Related Catalog
References

[1]. Geibel S, et al. Conformational dynamics of the Na+/K+-ATPase probed by voltage clamp fluorometry. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):964-9.

[2]. Loo DD, et al. Conformational changes couple Na+ and glucose transport. Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7789-94.

 Chemical & Physical Properties

Molecular Formula C28H23N3O5
Molecular Weight 481.49900
Exact Mass 481.16400
PSA 97.13000
LogP 3.52400

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases R22
Safety Phrases S36
RIDADR NONH for all modes of transport

 Synonyms

Tetramethylrhodamine-6-maleimide
MFCD01311092