Eleutherobin
Modify Date: 2025-08-27 01:09:50
Eleutherobin structure
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Common Name | Eleutherobin | ||
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| CAS Number | 174545-76-7 | Molecular Weight | 656.76300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H48N2O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EleutherobinEleutherobin is a potent β-microtubule inhibitor with an IC50 value of 2 μM. Eleutherobin can be isolated from a marine soft coral. Eleutherobin has cytotoxic activity against cancer cells with similar potency to that of Paclitaxel (HY-B0015). Anticancer activity[1][2]. |
| Name | eleutherobin |
|---|---|
| Synonym | More Synonyms |
| Description | Eleutherobin is a potent β-microtubule inhibitor with an IC50 value of 2 μM. Eleutherobin can be isolated from a marine soft coral. Eleutherobin has cytotoxic activity against cancer cells with similar potency to that of Paclitaxel (HY-B0015). Anticancer activity[1][2]. |
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| Related Catalog | |
| Target |
IC50: 2 μM (β-microtubule)[1] |
| In Vitro | Eleutherobin (0-600 nM; 72 h) exhibits cytotoxic activity against HCT116, HCT116 (VM46), A2780 and A2780/Tax22[1]. Cell Cytotoxicity Assay[1] Cell Line: HCT116, HCT116 (VM46), A2780 and A2780/Tax22 Concentration: 0-600 nM Incubation Time: 72 h Result: Exhibited cytotoxic activity against HCT116, HCT116 (VM46), A2780 and A2780/Tax22 with IC50s of 10.7 nM, 554 nM, 13.7 nM and 59 nM. |
| References |
| Molecular Formula | C35H48N2O10 |
|---|---|
| Molecular Weight | 656.76300 |
| Exact Mass | 656.33100 |
| PSA | 147.80000 |
| LogP | 3.24400 |
| eleutherobin |