dehydroabietic acid

Modify Date: 2025-08-21 18:16:16

dehydroabietic acid structure	Common Name	dehydroabietic acid
	CAS Number	1740-19-8	Molecular Weight	300.435
	Density	1.1±0.1 g/cm3	Boiling Point	425.1±34.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₈O₂	Melting Point	174-176ºC
	MSDS	Chinese USA	Flash Point	202.5±20.3 °C
	Symbol	GHS06, GHS09	Signal Word	Danger

Use of dehydroabietic acid

Dehydroabietic acid possesses antiviral activity[1].

Name	dehydroabietic acid
Synonym	More Synonyms

Description	Dehydroabietic acid possesses antiviral activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Fonseca T, et al. Synthesis and antiviral evaluation of benzimidazoles, quinoxalines and indoles from dehydroabietic acid. Bioorg Med Chem. 2004 Jan 2;12(1):103-12.

Density	1.1±0.1 g/cm3
Boiling Point	425.1±34.0 °C at 760 mmHg
Melting Point	174-176ºC
Molecular Formula	C₂₀H₂₈O₂
Molecular Weight	300.435
Flash Point	202.5±20.3 °C
Exact Mass	300.208923
PSA	37.30000
LogP	6.35
Appearance of Characters	NA
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.540
Storage condition	?20°C

dehydroabietic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP8710000

CHEMICAL NAME :: Podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl-

CAS REGISTRY NUMBER :: 1740-19-8

BEILSTEIN REFERENCE NO. :: 2059290

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C20-H28-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1710 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - ataxia

REFERENCE :: BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 18,42,1977 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8400 mg/kg/28D-C

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Metabolism (Intermediary) - Plasma proteins not involving coagulation

REFERENCE :: BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 18,42,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2653 No. of Facilities: 1630 (estimated) No. of Industries: 16 No. of Occupations: 20 No. of Employees: 13811 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2653 No. of Facilities: 394 (estimated) No. of Industries: 8 No. of Occupations: 12 No. of Employees: 14625 (estimated) No. of Female Employees: 4688 (estimated)

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301-H410
Precautionary Statements	P273-P301 + P310-P501
Hazard Codes	T,N
Risk Phrases	25-50
Safety Phrases	45-61
RIDADR	UN 2811 6.1 / PGIII

Precursor 10
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DownStream 7
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Development of ultrasonic-assisted closed in-syringe extraction and derivatization for the determination of labile abietic acid and dehydroabietic acid in cosmetics.

J. Chromatogr. A. 1371 , 20-9, (2014)

Two resin acids, abietic acid (AA) and dehydroabietic acid (DHAA), in cosmetics may cause allergy or toxicoderma, but remain inaccurately investigated due to their lability. In this work, an accurate,...

Disproportionated rosin dehydroabietic acid in neoprene surgical gloves.

Dermatitis 21(3) , 157-9, (2010)

Allergic contact dermatitis (ACD) is a well-recognized immune-mediated disease often associated with the use of vulcanization accelerator-containing latex and nitrile gloves. Potential contact allerge...

Synthesis and antibacterial evaluation of New N-acylhydrazone derivatives from dehydroabietic acid.

Molecules 17(4) , 4634-50, (2012)

A series of new N-acylhydrazone derivatives were synthesized in good yields through the reactions of dehydroabietic acid hydrazide with a variety of substituted arylaldehydes. The structures of the sy...

dehydroabietic acid

abietic acid, dehydro-

1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic acid

(+)-Dehydroabietic acid

1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)-

Abieta-8(14),9(11),12-trien-18-oic acid

Abieta-8,11,13-trien-18-oic acid,Dehydroabietate

EINECS 217-102-8

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dehydroabietic acid

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