TrkA-IN-1

Modify Date: 2024-01-20 17:25:18

TrkA-IN-1 structure	Common Name	TrkA-IN-1
	CAS Number	1680179-43-4	Molecular Weight	392.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₀N₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TrkA-IN-1

TrkA-IN-1 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 of 99 nM in a cell-based assay. TrkA-IN-1 has analgesic activity[1].

Properties
Spectrum

Name	TrkA-IN-1

Description	TrkA-IN-1 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 of 99 nM in a cell-based assay. TrkA-IN-1 has analgesic activity[1].
Target	TrkA:99 nM (IC50) TrkB:81 μM (IC50) TrkC:25 μM (IC50)
References	[1]. Su HP , et al. Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E297-E306.

Description

TrkA-IN-1 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 of 99 nM in a cell-based assay. TrkA-IN-1 has analgesic activity[1].

Target

TrkA:99 nM (IC50)

TrkB:81 μM (IC50)

TrkC:25 μM (IC50)

References

[1]. Su HP , et al. Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E297-E306.

Molecular Formula	C₂₅H₂₀N₄O
Molecular Weight	392.45

TrkA-IN-1

Use of TrkA-IN-1

Names

TrkA-IN-1 Biological Activity

Chemical & Physical Properties