JZP 430

Modify Date: 2024-01-10 21:19:03

JZP 430 structure	Common Name	JZP 430
	CAS Number	1672691-74-5	Molecular Weight	354.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₂₆N₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JZP 430

JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL)[1].

Name	JZP-430

Description	JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL)[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL Research Areas >> Metabolic Disease
Target	IC50: 44 nM (ABHD6, human)[1]
References	[1]. Patel JZ, et al. Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. ChemMedChem. 2015 Feb;10(2):253-65.

Molecular Formula	C₁₆H₂₆N₄O₃S
Molecular Weight	354.47

Hazard Codes	Xi

JZP 430

Use of JZP 430

Names

JZP 430 Biological Activity

Chemical & Physical Properties

Safety Information