JZP 430

Modify Date: 2025-08-27 17:25:46

JZP 430 Structure
JZP 430 structure
Common Name JZP 430
CAS Number 1672691-74-5 Molecular Weight 354.47
Density N/A Boiling Point N/A
Molecular Formula C16H26N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JZP 430


JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL)[1].

 Names

Name JZP-430

 JZP 430 Biological Activity

Description JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL)[1].
Related Catalog
Target

IC50: 44 nM (ABHD6, human)[1]

References

[1]. Patel JZ, et al. Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. ChemMedChem. 2015 Feb;10(2):253-65.

 Chemical & Physical Properties

Molecular Formula C16H26N4O3S
Molecular Weight 354.47

 Safety Information

Hazard Codes Xi
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