BTK inhibitor 4b
Modify Date: 2025-08-20 22:31:04
BTK inhibitor 4b structure
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Common Name | BTK inhibitor 4b | ||
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| CAS Number | 1646608-10-7 | Molecular Weight | 498.522 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H23FN8O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BTK inhibitor 4bBTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively; demonstrates significant efficacy in models in vivo and good ADME and safety profiles. |
| Name | BTK inhibitor 4b |
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| Description | BTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively; demonstrates significant efficacy in models in vivo and good ADME and safety profiles. |
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| References | References 1. Kawahata W, et al. J Med Chem. 2018 Oct 11;61(19):8917-8933. View Related Products by Target BTK |
| Molecular Formula | C26H23FN8O2 |
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| Molecular Weight | 498.522 |
| InChIKey | RQYDQAPLARKISN-UHFFFAOYSA-N |
| SMILES | Cn1cc(Nc2nc(N)nc(-c3cccc(-n4ccc5cc(C6CC6)cc(F)c5c4=O)c3CO)n2)cn1 |