BTK inhibitor 10

Modify Date: 2025-08-26 12:04:54

BTK inhibitor 10 Structure
BTK inhibitor 10 structure
Common Name BTK inhibitor 10
CAS Number 2241732-30-7 Molecular Weight 441.491
Density N/A Boiling Point N/A
Molecular Formula C25H23N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BTK inhibitor 10


BTK-030 is a novel BTK inhibitor.

 Names

Name BTK-030

 BTK inhibitor 10 Biological Activity

Description BTK-030 is a novel BTK inhibitor.
Related Catalog
Target

IC50: Bruton kinase (BTK)[1]

In Vivo BTK inhibitor 10 (oral gavage; 30 mg/kg; 21 days; once daily) has a significant improvement in arthritis symptoms in CIA mice. The damage of each of the 4 paws in mice is divided into 0-4 to calculate the total score of the limbs. After 21 days’ oral treatment, BTK030 reduces the arthritic score to 3.62 while the control group shows a value of 8.33[1]. Animal Model: DBA/1J mice injected with collagen as a CIA model[1] Dosage: 30 mg/kg Administration: oral gavage; 21 days; once daily Result: Decreased arthritis scores significantly when it compares to control group.
References

[1]. HuiJun Yin, et al. Pyrrolo-aromatic heterocyclic compound, preparation method therefor, and medical use thereof. Patent WO2018145525

 Chemical & Physical Properties

Molecular Formula C25H23N5O3
Molecular Weight 441.491
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