Name | BTK inhibitor 4b |
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Description | BTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively; demonstrates significant efficacy in models in vivo and good ADME and safety profiles. |
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References | References 1. Kawahata W, et al. J Med Chem. 2018 Oct 11;61(19):8917-8933. View Related Products by Target BTK |
Molecular Formula | C26H23FN8O2 |
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Molecular Weight | 498.522 |