BTK inhibitor 4b
Names
[ CAS No. ]:
1646608-10-7
[ Name ]:
BTK inhibitor 4b
Biological Activity
[Description]:
BTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively; demonstrates significant efficacy in models in vivo and good ADME and safety profiles.
[References]
References 1. Kawahata W, et al. J Med Chem. 2018 Oct 11;61(19):8917-8933. View Related Products by Target BTK
Chemical & Physical Properties
[ Molecular Formula ]:
C26H23FN8O2
[ Molecular Weight ]:
498.522
Related Compounds
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