hnNOS-IN-3
Modify Date: 2025-08-27 00:40:12
hnNOS-IN-3 structure
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Common Name | hnNOS-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 163490-78-6 | Molecular Weight | 284.73 | |
| Density | 1.27 g/cm3 | Boiling Point | 322.3ºC at 760 mmHg | |
| Molecular Formula | C10H12ClF3N2S | Melting Point | 143-147ºC | |
| MSDS | N/A | Flash Point | 148.8ºC | |
Use of hnNOS-IN-3hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively[1]. |
| Name | etpi hcl |
|---|---|
| Synonym | More Synonyms |
| Description | hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
nNOS:0.32 μM (Ki) eNOS:9.4 μM (Ki) iNOS:37 μM (Ki) |
| References |
| Density | 1.27 g/cm3 |
|---|---|
| Boiling Point | 322.3ºC at 760 mmHg |
| Melting Point | 143-147ºC |
| Molecular Formula | C10H12ClF3N2S |
| Molecular Weight | 284.73 |
| Flash Point | 148.8ºC |
| Exact Mass | 284.036194 |
| PSA | 61.18000 |
| LogP | 4.77990 |
| Vapour Pressure | 0.000281mmHg at 25°C |
| Safety Phrases | S24/25 |
|---|
| Carbamimidothioic acid, N'-[4-(trifluoromethyl)phenyl]-, ethyl ester, hydrochloride (1:1) |
| TFPI HCL |
| EPIT HCL |
| MFCD01320531 |
| Ethyl N'-[4-(trifluoromethyl)phenyl]carbamimidothioate hydrochloride (1:1) |
| TFPI hydrochloride |
| SEPIT HCL |
| ETPI,HYDROCHLORIDE |