MQAE

Modify Date: 2024-01-06 10:13:18

MQAE Structure
MQAE structure
Common Name MQAE
CAS Number 162558-52-3 Molecular Weight 326.18600
Density N/A Boiling Point N/A
Molecular Formula C14H16BrNO3 Melting Point 177-179ºC(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of MQAE


MQAE is a fluorescent indicator that is quenched via collision with chloride, and is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells.

 Names

Name 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide
Synonym More Synonyms

 MQAE Biological Activity

Description MQAE is a fluorescent indicator that is quenched via collision with chloride, and is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells.
Related Catalog
In Vitro Bath-applied to acute brain slices, MQAE provides high-quality labeling of neuronal cells and their processes[1]. MQAE fluorescence is adequate and comparable method for measuring cAMP-dependent chloride transport in individual cells[2]. MQAE can be used to measure intracellular chloride concentration in primary cultures of rat aortic smooth muscle cells (VSMC)[3].
References

[1]. Kovalchuk Y, et al. Two-photon chloride imaging using MQAE in vitro and in vivo. Cold Spring Harb Protoc. 2012 Jul 1;2012(7):778-85.

[2]. Andersson C, et al. Determination of chloride efflux by X-ray microanalysis versus MQAE-fluorescence. Microsc Res Tech. 2002 Dec 15;59(6):531-5.

[3]. Koncz C, et al. Use of MQAE for measurement of intracellular [Cl-] in cultured aortic smooth muscle cells. Am J Physiol. 1994 Dec;267(6 Pt 2):H2114-23.

 Chemical & Physical Properties

Melting Point 177-179ºC(lit.)
Molecular Formula C14H16BrNO3
Molecular Weight 326.18600
Exact Mass 325.03100
PSA 39.41000
Storage condition -20℃

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
RIDADR NONH for all modes of transport
HS Code 2933499090

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles13

More Articles
Synthesis and characterization of improved chloride-sensitive fluorescent indicators for biological applications.

Anal. Biochem. 178 , 355, (1989)

A class of N-substituted quinoline compounds has been introduced recently for the fluorescence measurement of Cl concentration in biological preparations. The most Cl-sensitive compound was 6-methoxy-...

Hypoxia inhibits colonic ion transport via activation of AMP kinase.

Ann. Surg. 254 , 957-963, (2011)

Mucosal hypoxia is a common endpoint for many pathological processes including ischemic colitis, colonic obstruction and anastomotic failure. Previous studies suggest that hypoxia modulates colonic mu...

The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders.

Hepatology 50 , 861-870, (2009)

TGR5 (Gpbar-1) is a plasma membrane-bound, G protein-coupled receptor for bile acids. TGR5 messenger RNA (mRNA) has been detected in many tissues, including rat cholangiocytes and mouse gallbladder. A...

 Synonyms

(6-Methoxyquinolinio)acetic acid ethyl ester bromide,MQAE
(6-Methoxyquinolinio)acetic acid ethyl ester bromide MQAE
ethyl 2-(6-methoxyquinolin-1-ium-1-yl)acetate,bromide
MQAE
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: MQAE
  • Price: $300.0/500mg $550.0/1g $900.0/2g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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Price: $66/10mM*1mLinDMSO

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