GNE-8505

Modify Date: 2024-01-10 12:19:10

Use of GNE-8505

GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK)[1].

Name	GNE-8505

Description	GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK)[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> MAPK/ERK Pathway >> MAP3K
Target	DLK[1]
References	[1]. Le Pichon CE, et al. Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease. Sci Transl Med. 2017 Aug 16;9(403). pii: eaag0394.

Molecular Formula	C₂₁H₂₄F₃N₅O
Molecular Weight	419.44