Esomeprazole
Modify Date: 2024-01-02 18:03:19
Esomeprazole structure
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Common Name | Esomeprazole | ||
|---|---|---|---|---|
| CAS Number | 161973-10-0 | Molecular Weight | 713.121 | |
| Density | N/A | Boiling Point | 600ºC at 760 mmHg | |
| Molecular Formula | C34H36MgN6O6S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 316.7ºC | |
Use of EsomeprazoleEsomeprazole magnesium is an inhibitor of H+, K+-ATPase, effectively used in the research of upper intestinal disorder. |
| Name | esomeprazole magnesium |
|---|---|
| Synonym | More Synonyms |
| Description | Esomeprazole magnesium is an inhibitor of H+, K+-ATPase, effectively used in the research of upper intestinal disorder. |
|---|---|
| Related Catalog | |
| Target |
H+, K+-ATPase[1] |
| In Vitro | Esomeprazole magnesium is an inhibitor of H+, K+-ATPase[1]. |
| In Vivo | Esomeprazole magnesium (0.5, 5, 50 mg/kg/day, p.o.) produces increased gastric total antioxidant capacity, decreases gastric lipid peroxide levels, significantly increases superoxide dismutase levels, but shows no obvious effect on colonic lipid peroxide levels in mice[1]. |
| Animal Admin | Mice[1] In this 10-day supplementation experiment, mice (n = 10/group) receive the following: 1) as a control group, only the vehicle for dissolution of Esomeprazole (PEG-400) given orally once daily by gastric gavage; 2) Esomeprazole 0.5 mg/kg in an equivalent volume of PEG-400 given orally once daily by gastric lavage; 3) Esomeprazole 5 mg/kg in an equivalent volume of PEG-400 given orally once daily by gastric lavage; and 4) Esomeprazole 50 mg/kg in an equivalent volume of PEG-400 given orally once daily by gastric lavage[1]. |
| References |
| Boiling Point | 600ºC at 760 mmHg |
|---|---|
| Molecular Formula | C34H36MgN6O6S2 |
| Molecular Weight | 713.121 |
| Flash Point | 316.7ºC |
| Exact Mass | 712.198792 |
| PSA | 186.82000 |
| LogP | 6.78900 |
| Vapour Pressure | 2.35E-14mmHg at 25°C |
| Storage condition | -20℃ |
| (-)-Omeprazole magnesium |
| Nexium |
| H-199/18 |
| omeprazole magnesium |
| EsMeprazole Magne-siuM Trihydrate |
| sulfonium, hydroxy(6-methoxy-1H-benzimidazol-2-yl)[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-, inner salt, magnesium salt (2:1) |
| H 199/18 |
| (T-4-(S),(S))-Bis(5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazolato)magnesium |
| (S)-Omeprazole magnesium |
| (T-4)-Bis(5-methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl-kO)-1H-benzimidazolato-kN1)magnesium |
| Magnesium bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}benzimidazol-1-ide) |
| Esomeprazole magnesium |
| 1H-Benzimidazole, 5-methoxy-2-[(S)-[(1S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, magnesium salt (2:1) |
| Magnesium bis{(6-methoxybenzimidazol-1-id-2-yl)[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfoniumolate} |
| Magnesium bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) |
| Esomeprazole |