ML318
Modify Date: 2025-08-27 00:44:05
ML318 structure
|
Common Name | ML318 | ||
|---|---|---|---|---|
| CAS Number | 1610516-67-0 | Molecular Weight | 280.22 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H8F4N2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of ML318ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions[1]. |
| Name | ML318 |
|---|
| Description | ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 20 nM (PvdQ acylase)[1] |
| References |
| Molecular Formula | C14H8F4N2 |
|---|---|
| Molecular Weight | 280.22 |
| InChIKey | DXQNDKQUHKVTTC-UHFFFAOYSA-N |
| SMILES | N#CC(c1ccc(F)cc1)c1cccc(C(F)(F)F)n1 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 + P330 |
| Hazard Codes | Xi |
| RIDADR | UN 2811 6.1 / PGIII |