Auristatin E
Modify Date: 2024-01-02 22:46:20
Auristatin E structure
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Common Name | Auristatin E | ||
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| CAS Number | 160800-57-7 | Molecular Weight | 732.005 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 871.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C40H69N5O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 480.6±34.3 °C | |
Use of Auristatin EAuristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. |
| Name | N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide |
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| Synonym | More Synonyms |
| Description | Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 871.0±65.0 °C at 760 mmHg |
| Molecular Formula | C40H69N5O7 |
| Molecular Weight | 732.005 |
| Flash Point | 480.6±34.3 °C |
| Exact Mass | 731.519714 |
| LogP | 4.75 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.519 |
| Storage condition | 2-8℃ |
| N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide |
| L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl- |
| MFCD25976744 |
| Auristatin E |