ML 278

Modify Date: 2024-02-05 01:05:57

ML 278 Structure
ML 278 structure
Common Name ML 278
CAS Number 1604821-43-3 Molecular Weight 453.513
Density N/A Boiling Point N/A
Molecular Formula C23H23N3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ML 278


ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM; a plasma-stable, noncytotoxic probe that exhibits moderate metabolic stability, thus displaying improved properties for in vitro and in vivo studies; increases the binding of HDL to SR-BI.

 Names

Name ML 278

 ML 278 Biological Activity

Description ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM; a plasma-stable, noncytotoxic probe that exhibits moderate metabolic stability, thus displaying improved properties for in vitro and in vivo studies; increases the binding of HDL to SR-BI.
References References 1. Dockendorff C, et al. ACS Med Chem Lett. 2015 Feb 2;6(4):375-380. View Related Products by Target Scavenger Receptor

 Chemical & Physical Properties

Molecular Formula C23H23N3O5S
Molecular Weight 453.513
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