ML 278

Names

[ Name ]:
ML 278

Biological Activity

[Description]:

ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM; a plasma-stable, noncytotoxic probe that exhibits moderate metabolic stability, thus displaying improved properties for in vitro and in vivo studies; increases the binding of HDL to SR-BI.

[References]

References 1. Dockendorff C, et al. ACS Med Chem Lett. 2015 Feb 2;6(4):375-380. View Related Products by Target Scavenger Receptor

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₃N₃O₅S

[ Molecular Weight ]:
453.513

Related Compounds

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