4-Desmethyl Istradefylline

Modify Date: 2024-01-11 07:39:13

4-Desmethyl Istradefylline Structure
4-Desmethyl Istradefylline structure
Common Name 4-Desmethyl Istradefylline
CAS Number 160434-48-0 Molecular Weight 370.40200
Density N/A Boiling Point N/A
Molecular Formula C19H22N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-Desmethyl Istradefylline


4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease[1].

 Names

Name (E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione
Synonym More Synonyms

 4-Desmethyl Istradefylline Biological Activity

Description 4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease[1].
Related Catalog
References

[1]. Chen JF, et al. Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease. J Neurosci. 2001 May 15;21(10):RC143.

 Chemical & Physical Properties

Molecular Formula C19H22N4O4
Molecular Weight 370.40200
Exact Mass 370.16400
PSA 91.28000
LogP 1.82110

 Synonyms

4-Desmethyl Istradefylline