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4-Desmethyl Istradefylline

Names

[ CAS No. ]:
160434-48-0

[ Name ]:
4-Desmethyl Istradefylline

[Synonym ]:
4-Desmethyl Istradefylline

Biological Activity

[Description]:

4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Chen JF, et al. Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease. J Neurosci. 2001 May 15;21(10):RC143.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H22N4O4

[ Molecular Weight ]:
370.40200

[ Exact Mass ]:
370.16400

[ PSA ]:
91.28000

[ LogP ]:
1.82110

Related Compounds