160434-48-0

160434-48-0 structure

Name: 4-Desmethyl Istradefylline
Chemical Name: (E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione
CAS Number: 160434-48-0
Molecular Formula: C₁₉H₂₂N₄O₄
Molecular Weight: 370.40200
Catalog: Research Areas Neurological Disease
Create Date: 2016-01-03 10:05:53
Modify Date: 2025-08-20 20:11:03
4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease[1].

Name	(E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione
Synonyms	4-Desmethyl Istradefylline

Description	4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Chen JF, et al. Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease. J Neurosci. 2001 May 15;21(10):RC143.