m-PEG4-CH2COOH

Modify Date: 2024-01-09 19:04:52

m-PEG4-CH2COOH Structure
m-PEG4-CH2COOH structure
Common Name m-PEG4-CH2COOH
CAS Number 16024-66-1 Molecular Weight 266.28800
Density 1.125g/cm3 Boiling Point 379.6ºC at 760 mmHg
Molecular Formula C11H22O7 Melting Point N/A
MSDS N/A Flash Point 137.1ºC

 Use of m-PEG4-CH2COOH


m-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]acetic acid
Synonym More Synonyms

 m-PEG4-CH2COOH Biological Activity

Description m-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. TaoDeng, et al. Monodisperse oligoethylene glycols modified Propofol prodrugs. Bioorganic & Medicinal Chemistry Letters.

 Chemical & Physical Properties

Density 1.125g/cm3
Boiling Point 379.6ºC at 760 mmHg
Molecular Formula C11H22O7
Molecular Weight 266.28800
Flash Point 137.1ºC
Exact Mass 266.13700
PSA 83.45000
Vapour Pressure 8.24E-07mmHg at 25°C
Index of Refraction 1.447

 Safety Information

Hazard Codes Xi
HS Code 2918990090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

3,6,9,12,15-pentoxahexadecanoic acid
MPEG4-acetic acid
(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)acetic acid
3,6,9,12,15-Pentaoxahexadecansaeure
EINECS 240-163-7
3,6,9,12,15-Pentaoxahexadecanoicacid
2,5,8,11,14-Pentaoxahexadecan-16-oic acid