M-PEG4-DBCO

Modify Date: 2025-08-25 10:24:54

M-PEG4-DBCO structure	Common Name	M-PEG4-DBCO
	CAS Number	2228857-36-9	Molecular Weight	494.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₄N₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of M-PEG4-DBCO

m-PEG4-NH-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG4-NH-DBCO
Synonym	More Synonyms

Description	m-PEG4-NH-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₈H₃₄N₂O₆
Molecular Weight	494.58
InChIKey	CUEOILOXVJZHLK-UHFFFAOYSA-N
SMILES	COCCOCCOCCOCCNC(=O)CCC(=O)N1Cc2ccccc2C#Cc2ccccc21

MFCD31654033

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