Tamoxifen-d5

Modify Date: 2024-01-11 18:46:23

Tamoxifen-d5 structure	Common Name	Tamoxifen-d5
	CAS Number	157698-32-3	Molecular Weight	376.54500
	Density	1.057g/cm3	Boiling Point	482.3ºC at 760mmHg
	Molecular Formula	C₂₆H₂₄D₅NO	Melting Point	N/A
	MSDS	N/A	Flash Point	140ºC

Use of Tamoxifen-d5

Tamoxifen-d5 (ICI 47699-d5) is a deuterium labeled Tamoxifen. Tamoxifen (ICI 47699) is a selective estrogen receptor modulator (SERM). Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity[1][2].

Name	N,N-dimethyl-2-[4-[(Z)-3,3,4,4,4-pentadeuterio-1,2-diphenylbut-1-enyl]phenoxy]ethanamine
Synonym	More Synonyms

Description	Tamoxifen-d5 (ICI 47699-d5) is a deuterium labeled Tamoxifen. Tamoxifen (ICI 47699) is a selective estrogen receptor modulator (SERM). Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity[1][2].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	Estrogen receptor HSP90
References	[1]. Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med. 1998 Nov 26;339(22):1609-18. [2]. Zhao R, et al. Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. PLoS One. 2010 Apr 1;5(4):e9934.

Density	1.057g/cm3
Boiling Point	482.3ºC at 760mmHg
Molecular Formula	C₂₆H₂₄D₅NO
Molecular Weight	376.54500
Flash Point	140ºC
Exact Mass	376.25600
PSA	12.47000
LogP	5.99610
Vapour Pressure	1.85E-09mmHg at 25°C
Index of Refraction	1.582

(E/Z)-Mammaton-d5

Novaldex-d5

Z-Tamoxifen-d5

Mammaton-d5

(E/Z)-Novaldex-d5

(E/Z)-Tamoxifen-d5

trans-Tamoxifen-d5

Tamoxifen-d5

Tamoxifen-d5

Use of Tamoxifen-d5

Names

Tamoxifen-d5 Biological Activity

Chemical & Physical Properties

Synonyms