157698-32-3

157698-32-3 structure

Name: Tamoxifen-d5
Chemical Name: N,N-dimethyl-2-[4-[(Z)-3,3,4,4,4-pentadeuterio-1,2-diphenylbut-1-enyl]phenoxy]ethanamine
CAS Number: 157698-32-3
Molecular Formula: C₂₆H₂₄D₅NO
Molecular Weight: 376.54500
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-09-13 21:18:25
Modify Date: 2025-08-25 10:56:53
Tamoxifen-d5 (ICI 47699-d5) is a deuterium labeled Tamoxifen. Tamoxifen (ICI 47699) is a selective estrogen receptor modulator (SERM). Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity[1][2].

Name	N,N-dimethyl-2-[4-[(Z)-3,3,4,4,4-pentadeuterio-1,2-diphenylbut-1-enyl]phenoxy]ethanamine
Synonyms	(E/Z)-Mammaton-d5 Novaldex-d5 Z-Tamoxifen-d5 Mammaton-d5 (E/Z)-Novaldex-d5 (E/Z)-Tamoxifen-d5 trans-Tamoxifen-d5 Tamoxifen-d5

Description	Tamoxifen-d5 (ICI 47699-d5) is a deuterium labeled Tamoxifen. Tamoxifen (ICI 47699) is a selective estrogen receptor modulator (SERM). Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity[1][2].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	Estrogen receptor HSP90
References	[1]. Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med. 1998 Nov 26;339(22):1609-18. [2]. Zhao R, et al. Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. PLoS One. 2010 Apr 1;5(4):e9934.