CHLORO(TRIETHYLPHOSPHINE)GOLD(I)

Modify Date: 2024-01-09 12:41:01

CHLORO(TRIETHYLPHOSPHINE)GOLD(I) Structure
CHLORO(TRIETHYLPHOSPHINE)GOLD(I) structure
Common Name CHLORO(TRIETHYLPHOSPHINE)GOLD(I)
CAS Number 15529-90-5 Molecular Weight 350.57700
Density N/A Boiling Point 210ºC0.03 mm Hg(lit.)
Molecular Formula C6H15AuClP Melting Point 84-86ºC(lit.)
MSDS Chinese USA Flash Point 27.2ºC
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name chloro(triethylphosphine)gold(i)
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 210ºC0.03 mm Hg(lit.)
Melting Point 84-86ºC(lit.)
Molecular Formula C6H15AuClP
Molecular Weight 350.57700
Flash Point 27.2ºC
Exact Mass 350.02700
PSA 13.59000
LogP 3.21500
Appearance of Characters crystal | white to pink

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MD5431000
CHEMICAL NAME :
Gold, chloro(triethylphosphine)-
CAS REGISTRY NUMBER :
15529-90-5
LAST UPDATED :
199112
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H15-Au-Cl-P
MOLECULAR WEIGHT :
350.60
WISWESSER LINE NOTATION :
G-AU-UP3&3&3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
79 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
68 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
92560 ug/kg
SEX/DURATION :
female 6-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
46280 ug/kg
SEX/DURATION :
female 6-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human Cells - not otherwise specified
DOSE/DURATION :
37500 nmol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 34,3243,1985

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301 + H311 + H331-H315-H319-H335
Precautionary Statements P261-P280-P301 + P310-P305 + P351 + P338-P311
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T: Toxic;
Risk Phrases R23/24/25
Safety Phrases 26-28-36/37/39-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS MD5431000
Packaging Group III
Hazard Class 6.1(b)

 Articles21

More Articles
Synthesis of thionato(triethylphosphine) gold(I) complexes:analogues of "auranofin," an antiarthritic drug.

J. Inorg. Biochem. 38(2) , 95-100, (1990)

New compounds having the formula [L-Au-PEt3]Cl (where L = imidazolidine-2-thione(Imt) and 1,3-Diazinane-2-thione(Diaz)) are synthesized. They are characterized by elemental analysis, infrared, 13C and...

Inhibition of human phospholipase C by aurothiomalate and (triethylphosphine) gold complexes.

Arzneimittelforschung 42(3) , 328-33, (1992)

The effect of several gold complexes on the activity of phospholipase C from human blood platelets was studied in vitro. Aurothiomalate and auranofin--2 agents used for the chrysotherapy of rheumatoid...

The structural flexibility of ferric cytochrome c: regulation of the spin-state equilibrium by an anti-arthritic gold(I) compound at neutral pH.

FEBS Lett. 116(2) , 227-30, (1980)

 Synonyms

Gold,chloro(triethylphosphine)
[Au(PEt3)Cl]
chloro(triethylphosphine)-gol
TRIETHYLPHOSPHINEGOLD I CHLORIDE
chloro(triethylphosphine)gold
[AuCl(PEt3)]
PEt3 gold(I) chloro complex
EINECS 239-572-3
MFCD00013205
Triethylphosphineaurous chloride
triethylphosphinegold