4’-Methylguanosine

Modify Date: 2025-08-26 18:18:06

4’-Methylguanosine Structure
4’-Methylguanosine structure
Common Name 4’-Methylguanosine
CAS Number 153186-32-4 Molecular Weight 297.27
Density 2.0±0.1 g/cm3 Boiling Point 733.1±70.0 °C at 760 mmHg
Molecular Formula C11H15N5O5 Melting Point N/A
MSDS N/A Flash Point 397.2±35.7 °C

 Use of 4’-Methylguanosine


4’-Methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-Amino-9-[5-deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-3,9-dihydro-6H-purin-6-one
Synonym More Synonyms

 4’-Methylguanosine Biological Activity

Description 4’-Methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 733.1±70.0 °C at 760 mmHg
Molecular Formula C11H15N5O5
Molecular Weight 297.27
Flash Point 397.2±35.7 °C
Exact Mass 297.107330
LogP 0.34
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.860

 Synonyms

2-Amino-9-[5-deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-3,9-dihydro-6H-purin-6-one
6H-Purin-6-one, 2-amino-9-[5-deoxy-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-3,9-dihydro-
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