4’-Methylguanosine

Names

[ CAS No. ]:
153186-32-4

[ Name ]:
4’-Methylguanosine

[Synonym ]:
2-Amino-9-[5-deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-3,9-dihydro-6H-purin-6-one
6H-Purin-6-one, 2-amino-9-[5-deoxy-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-3,9-dihydro-

Biological Activity

[Description]:

4’-Methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
733.1±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H15N5O5

[ Molecular Weight ]:
297.27

[ Flash Point ]:
397.2±35.7 °C

[ Exact Mass ]:
297.107330

[ LogP ]:
0.34

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.860

Related Compounds

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