4’-Methyl-5-methyluridine

Modify Date: 2025-08-27 08:25:56

4’-Methyl-5-methyluridine Structure
4’-Methyl-5-methyluridine structure
Common Name 4’-Methyl-5-methyluridine
CAS Number 152540-75-5 Molecular Weight 272.25
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C11H16N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4’-Methyl-5-methyluridine


4’-Methyl-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[5-Deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
Synonym More Synonyms

 4’-Methyl-5-methyluridine Biological Activity

Description 4’-Methyl-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C11H16N2O6
Molecular Weight 272.25
Exact Mass 272.100830
LogP -0.26
Index of Refraction 1.597

 Synonyms

2,4(1H,3H)-Pyrimidinedione, 1-[5-deoxy-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-
1-[5-Deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
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