4’-Methyl-5-methyluridine

Names

[ CAS No. ]:
152540-75-5

[ Name ]:
4’-Methyl-5-methyluridine

[Synonym ]:
2,4(1H,3H)-Pyrimidinedione, 1-[5-deoxy-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-
1-[5-Deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

Biological Activity

[Description]:

4’-Methyl-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C11H16N2O6

[ Molecular Weight ]:
272.25

[ Exact Mass ]:
272.100830

[ LogP ]:
-0.26

[ Index of Refraction ]:
1.597

Related Compounds

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