sulfo-NHS-acetate

Modify Date: 2025-08-27 09:47:51

sulfo-NHS-acetate Structure
sulfo-NHS-acetate structure
Common Name sulfo-NHS-acetate
CAS Number 152305-87-8 Molecular Weight 237.18700
Density 1.8g/cm3 Boiling Point N/A
Molecular Formula C6H7NO7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of sulfo-NHS-acetate


Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid
Synonym More Synonyms

 sulfo-NHS-acetate Biological Activity

Description Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.8g/cm3
Molecular Formula C6H7NO7S
Molecular Weight 237.18700
Exact Mass 236.99400
PSA 126.43000
Index of Refraction 1.583
InChIKey MDUQWFYJHRLNRN-UHFFFAOYSA-N
SMILES CC(=O)ON1C(=O)CC(S(=O)(=O)O)C1=O

 Safety Information

Hazard Codes Xi
HS Code 2925190090

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

Sulfo-nhs-acetate
BIM103
Sulfosuccinimidyl acetate
3-Pyrrolidinesulfonicacid,1-(acetyloxy)-2,5-dioxo
1-Acetoxy-2,5-dioxopyrrolidine-3-sulfonic acid
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