sulfo-NHS-acetate

Modify Date: 2024-01-14 17:19:56

sulfo-NHS-acetate Structure
sulfo-NHS-acetate structure
Common Name sulfo-NHS-acetate
CAS Number 152305-87-8 Molecular Weight 237.18700
Density 1.8g/cm3 Boiling Point N/A
Molecular Formula C6H7NO7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of sulfo-NHS-acetate


Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid
Synonym More Synonyms

 sulfo-NHS-acetate Biological Activity

Description Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.8g/cm3
Molecular Formula C6H7NO7S
Molecular Weight 237.18700
Exact Mass 236.99400
PSA 126.43000
Index of Refraction 1.583

 Safety Information

Hazard Codes Xi
HS Code 2925190090

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

Sulfo-nhs-acetate
BIM103
Sulfosuccinimidyl acetate
3-Pyrrolidinesulfonicacid,1-(acetyloxy)-2,5-dioxo
1-Acetoxy-2,5-dioxopyrrolidine-3-sulfonic acid
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