1821017-46-2

1821017-46-2 structure
1821017-46-2 structure
  • Name: Methyltetrazine-Sulfo-NHS ester sodium
  • Chemical Name: Methyltetrazine-Sulfo-NHS ester sodium
  • CAS Number: 1821017-46-2
  • Molecular Formula: C15H12N5NaO7S
  • Molecular Weight: 429.34
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:48:29
  • Modify Date: 2024-01-01 21:14:35
  • Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methyltetrazine-Sulfo-NHS ester sodium
Description Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H12N5NaO7S
Molecular Weight 429.34
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