8-Bromo-2'-deoxyadenosine

Modify Date: 2024-01-02 13:28:35

8-Bromo-2'-deoxyadenosine structure	Common Name	8-Bromo-2'-deoxyadenosine
	CAS Number	14985-44-5	Molecular Weight	330.14
	Density	2.3g/cm3	Boiling Point	671ºC at 760mmHg
	Molecular Formula	C₁₀H₁₂BrN₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	359.6ºC

Use of 8-Bromo-2'-deoxyadenosine

8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	8-Bromo-2'-deoxyadenosine
Synonym	More Synonyms

Description	8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	2.3g/cm3
Boiling Point	671ºC at 760mmHg
Molecular Formula	C₁₀H₁₂BrN₅O₃
Molecular Weight	330.14
Flash Point	359.6ºC
Exact Mass	329.01200
PSA	119.31000
LogP	0.39290
Appearance of Characters	Powder \| White to Yellow
Vapour Pressure	6.41E-19mmHg at 25°C
Index of Refraction	1.898
Water Solubility	Soluble in DMSO or DMF