PF-05381941
Modify Date: 2025-09-28 20:11:46
PF-05381941 structure
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Common Name | PF-05381941 | ||
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| CAS Number | 1474022-02-0 | Molecular Weight | 466.545 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H26N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-05381941PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases; inhibits LPS-stimulated release of TNF-α from human peripheral mononuclear cells with IC50 of 8 nM. |
| Name | PF-05381941 |
|---|
| Description | PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases; inhibits LPS-stimulated release of TNF-α from human peripheral mononuclear cells with IC50 of 8 nM. |
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| References | References 1. Kilty I, et al. Future Med Chem. 2015;7(1):23-33. View Related Products by Target TAK1 |
| Molecular Formula | C27H26N6O2 |
|---|---|
| Molecular Weight | 466.545 |