PF-05381941

Names

[ Name ]:
PF-05381941

Biological Activity

[Description]:

PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases; inhibits LPS-stimulated release of TNF-α from human peripheral mononuclear cells with IC50 of 8 nM.

[References]

References 1. Kilty I, et al. Future Med Chem. 2015;7(1):23-33. View Related Products by Target TAK1

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₆N₆O₂

[ Molecular Weight ]:
466.545

Related Compounds

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