PF-05381941
Names
[ CAS No. ]:
1474022-02-0
[ Name ]:
PF-05381941
Biological Activity
[Description]:
PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases; inhibits LPS-stimulated release of TNF-α from human peripheral mononuclear cells with IC50 of 8 nM.
[References]
References 1. Kilty I, et al. Future Med Chem. 2015;7(1):23-33. View Related Products by Target TAK1
Chemical & Physical Properties
[ Molecular Formula ]:
C27H26N6O2
[ Molecular Weight ]:
466.545