BRD-7880
Modify Date: 2025-09-22 03:22:41
BRD-7880 structure
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Common Name | BRD-7880 | ||
|---|---|---|---|---|
| CAS Number | 1456542-69-0 | Molecular Weight | 590.677 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H38N4O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BRD-7880A potent and highly specific inhibitor of Aurora B and Aurora C with IC50 of 7 and 12 nM respectively, with less activity against Aurora A (IC50>2 uM); is far more selective than tozasertib (VX-680), substantially inhibiting (to < 25% control activity) only AURKB and AURKC in a panel of 308 kinases. |
| Name | BRD-7880 |
|---|
| Description | A potent and highly specific inhibitor of Aurora B and Aurora C with IC50 of 7 and 12 nM respectively, with less activity against Aurora A (IC50>2 uM); is far more selective than tozasertib (VX-680), substantially inhibiting (to < 25% control activity) only AURKB and AURKC in a panel of 308 kinases. |
|---|---|
| References | References 1. Yu C, et al. Nat Biotechnol. 2016 Apr;34(4):419-23. View Related Products by Target Aurora Kinase |
| Molecular Formula | C32H38N4O7 |
|---|---|
| Molecular Weight | 590.677 |
| InChIKey | NGRSXEMLDRQNMH-LPBFERMMSA-N |
| SMILES | COc1ccc(NC(=O)Nc2ccc3c(c2)C(=O)N(C(C)CO)CC(C)C(CN(C)Cc2ccc4c(c2)OCO4)O3)cc1 |