Waglerin-1

Modify Date: 2024-01-30 15:07:28

Use of Waglerin-1

Waglerin-1, a 22-amino acid peptide, is a competitive antagonist of the muscle nicotinic receptor (nAChR)[1].

Name	GGKPDLRPCHPPCHYIPRPKPR

Description	Waglerin-1, a 22-amino acid peptide, is a competitive antagonist of the muscle nicotinic receptor (nAChR)[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Target	nAChR[1]
References	[1]. Brian E Molles, et al. Identification of Residues at the α and ε Subunit Interfaces Mediating Species Selectivity of Waglerin-1 for Nicotinic Acetylcholine Receptors. J Biol Chem. 2002 Feb 15;277(7):5433-40. [2]. J H Ye, et al. Waglerin-1 inhibits GABAA current of neurons in the nucleus accumbens of neonatal rats. Brain Res. 1999 Aug 7;837(1-2):29-37.

Molecular Formula	C₁₁₂H₁₇₅N₃₇O₂₆S₂
Molecular Weight	2519.95

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