MCT1-IN-4a
Modify Date: 2024-04-07 17:57:17
MCT1-IN-4a structure
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Common Name | MCT1-IN-4a | ||
|---|---|---|---|---|
| CAS Number | 1448314-00-8 | Molecular Weight | 385.419 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H19NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MCT1-IN-4aMCT1-IN-4a is a potent, selective monocarboxylate transporter 1 (MCT1) inhibitor with IC50 of 90 nM; exhibits significant single agent activity in MCT1 expressing GL261-luc2 syngraft model, but not in MCT4 expressing MDA-MB-231 xenograft model; has good absorption, metabolic stability, and a low drug efflux ratio. |
| Name | MCT1-IN-4a |
|---|
| Description | MCT1-IN-4a is a potent, selective monocarboxylate transporter 1 (MCT1) inhibitor with IC50 of 90 nM; exhibits significant single agent activity in MCT1 expressing GL261-luc2 syngraft model, but not in MCT4 expressing MDA-MB-231 xenograft model; has good absorption, metabolic stability, and a low drug efflux ratio. |
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| References | References 1. Gurrapu S, et al. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3282-6. View Related Products by Target Monocarboxylate Transporter (MCT) |
| Molecular Formula | C24H19NO4 |
|---|---|
| Molecular Weight | 385.419 |