DMT-2'Fluoro-DG(IB) Amidite

Modify Date: 2024-01-06 22:54:52

DMT-2'Fluoro-DG(IB) Amidite Structure
DMT-2'Fluoro-DG(IB) Amidite structure
Common Name DMT-2'Fluoro-DG(IB) Amidite
CAS Number 144089-97-4 Molecular Weight 857.906
Density N/A Boiling Point N/A
Molecular Formula C44H53FN7O8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DMT-2'Fluoro-DG(IB) Amidite


DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine[1].

 Names

Name 2'-F-ibu-dG Phosphoramidite
Synonym More Synonyms

 DMT-2'Fluoro-DG(IB) Amidite Biological Activity

Description DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine[1].
Related Catalog
References

[1]. Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555.

 Chemical & Physical Properties

Molecular Formula C44H53FN7O8P
Molecular Weight 857.906
Exact Mass 857.367737
LogP 9.87

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synonyms

9-{(3ξ)-5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-threo-pentofuranosyl}-2-(isobutyrylamino)-1,9-dihydro-6H-purin-6-one
6H-Purin-6-one, 9-[(3ξ)-5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-threo-pentofuranosyl]-1,9-dihydro-2-[(2-methyl-1-oxoprop yl)amino]-