verazine

Modify Date: 2024-01-03 09:01:50

verazine Structure
verazine structure
Common Name verazine
CAS Number 14320-81-1 Molecular Weight 397.64
Density N/A Boiling Point N/A
Molecular Formula C27H43NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of verazine


Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases[1][2].

 Names

Name verazine
Synonym More Synonyms

 verazine Biological Activity

Description Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases[1][2].
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References

[1]. Cong Y, et al. Steroidal Alkaloids from Veratrum maackii Regel with Genotoxicity on Brain-Cell DNA in Mice. Helv Chim Acta. 2015, 98(4): 539-545.

[2]. Augustin MM, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015 Jun;82(6):991-1003.  

 Chemical & Physical Properties

Molecular Formula C27H43NO
Molecular Weight 397.64
Exact Mass 397.33400
PSA 32.59000
LogP 5.86890

 Synonyms

(3S,8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-17-[(S)-1-((S)-5-methyl-3,4,5,6-tetrahydro-pyridin-2-yl)-ethyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
Verazin, (25S)-22,26-Imino-Δ5,22,N-cholestadien-3β-ol
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