14320-81-1

14320-81-1 structure

Name: verazine
Chemical Name: verazine
CAS Number: 14320-81-1
Molecular Formula: C₂₇H₄₃NO
Molecular Weight: 397.64
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2018-01-29 19:40:50
Modify Date: 2024-01-03 09:01:50
Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases[1][2].

Name	verazine
Synonyms	(3S,8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-17-[(S)-1-((S)-5-methyl-3,4,5,6-tetrahydro-pyridin-2-yl)-ethyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol Verazin, (25S)-22,26-Imino-Δ5,22,N-cholestadien-3β-ol

Description	Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Neurological Disease
References	[1]. Cong Y, et al. Steroidal Alkaloids from Veratrum maackii Regel with Genotoxicity on Brain-Cell DNA in Mice. Helv Chim Acta. 2015, 98(4): 539-545. [2]. Augustin MM, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015 Jun;82(6):991-1003.