Sodium Oleate

Modify Date: 2025-08-20 20:22:06

Sodium Oleate structure	Common Name	Sodium Oleate
	CAS Number	143-19-1	Molecular Weight	304.443
	Density	0.9 g/cm3	Boiling Point	359.999ºC at 760 mmHg
	Molecular Formula	C₁₈H₃₃NaO₂	Melting Point	232-235 °C(lit.)
	MSDS	Chinese USA	Flash Point	270.099ºC

Use of Sodium Oleate

Sodium oleate (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium[1]. Sodium oleate is a Na+/K+ ATPase activator[2].

Name	sodium oleate
Synonym	More Synonyms

Description	Sodium oleate (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium[1]. Sodium oleate is a Na+/K+ ATPase activator[2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Metabolic Disease
Target	Na+/K+ ATPase[2]
In Vitro	Oleic acid is the most common monounsaturated fatty acids (FA) in human adipocytes and other tissues. Oleic acid prompts cell proliferation and migration in high metastatic cancer cells via enhancing β-oxidation mediated by AMPK activation. Oleic acid inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines[1].
References	[1]. Li S, et al. High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner. PLoS One. 2014 May 13;9(5):e97330. [2]. Jack-Hays MG, et al. Activation of Na+/K(+)-ATPase by fatty acids, acylglycerols, and related amphiphiles: structure-activity relationship. Biochim Biophys Acta. 1996 Feb 21;1279(1):43-8.

Density	0.9 g/cm3
Boiling Point	359.999ºC at 760 mmHg
Melting Point	232-235 °C(lit.)
Molecular Formula	C₁₈H₃₃NaO₂
Molecular Weight	304.443
Flash Point	270.099ºC
Exact Mass	304.237823
PSA	40.13000
LogP	4.77380
Storage condition	−20°C
Stability	Stable. Incompatible with strong oxidizing agents.

Sodium Oleate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RK1200000

CHEMICAL NAME :: Oleic acid, sodium salt

CAS REGISTRY NUMBER :: 143-19-1

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C18-H33-O2.Na

MOLECULAR WEIGHT :: 304.50

WISWESSER LINE NOTATION :: QV8U9 &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 152 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,327,1970

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 24,221,1925 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0760 No. of Facilities: 11635 (estimated) No. of Industries: 91 No. of Occupations: 92 No. of Employees: 122970 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0760 No. of Facilities: 8020 (estimated) No. of Industries: 88 No. of Occupations: 92 No. of Employees: 162242 (estimated) No. of Female Employees: 33454 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	RK1200000
HS Code	2916150000

oleic acid

CAS#:112-80-1

Sodium Oleate

CAS#:143-19-1

Literature: WO2007/6334 A1, ; Page/Page column 8 ;

Sodium laurate

CAS#:629-25-4

Water

CAS#:7732-18-5

1-Dodecanethiol

CAS#:112-55-0

phenylene-ethylene

CAS#:292638-84-7

Detail

Literature: Journal of the American Chemical Society, , vol. 74, p. 4419,4420

Precursor 4
CAS#:112-80-1 oleic acid CAS#:629-25-4 Sodium laurate CAS#:7732-18-5 Water CAS#:112-55-0 1-Dodecanethiol
DownStream 10
CAS#:1120-44-1 COPPER(II) OLEATE CAS#:5431-33-4 glycidyl oleate CAS#:4746-97-8 1,4-Dioxaspiro[... CAS#:14160-65-7 ethyl 8-oxo-1,4...
CAS#:3008-39-7 1,2-Cycloheptan... CAS#:4436-58-2 α-hydroxycycloh... CAS#:108-94-1 Cyclohexanone CAS#:142-17-6 CALCIUM OLEATE
CAS#:124-11-8 nonene CAS#:872-05-9 1-decene

HS Code	2916150000
Summary	2916150000 oleic, linoleic or linolenic acids, their salts and esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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Predicting the oral pharmacokinetic profiles of multiple-unit (pellet) dosage forms using a modeling and simulation approach coupled with biorelevant dissolution testing: case example diclofenac sodium.

Eur. J. Pharm. Biopharm. 87(2) , 236-43, (2014)

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Sodium oleate

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EINECS 205-591-0

Pionin D 951P

Approx

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China
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Sodium oleate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: SODIUM OLEATE 143-19-1
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
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