triptoquinonoic acid a

Modify Date: 2024-01-12 13:39:15

triptoquinonoic acid a Structure
triptoquinonoic acid a structure
Common Name triptoquinonoic acid a
CAS Number 142950-86-5 Molecular Weight 328.40
Density 1.21g/cm3 Boiling Point 489.6ºC at 760mmHg
Molecular Formula C20H24O4 Melting Point N/A
MSDS N/A Flash Point 264ºC

 Use of triptoquinonoic acid a


Triptoquinone A, an interleukin 1 inhibitor, inhibits endomycin (LPS) or interleukin (IL-1β)-promoted induction of nitric oxide synthase (NOS) in vascular smooth muscle, thereby inhibiting Arg-induced vascular relaxation[1].

 Names

Name (4aS,10aS)-1,4a-dimethyl-5,8-dioxo-7-propan-2-yl-4,9,10,10a-tetrahydro-3H-phenanthrene-2-carboxylic acid
Synonym More Synonyms

 triptoquinonoic acid a Biological Activity

Description Triptoquinone A, an interleukin 1 inhibitor, inhibits endomycin (LPS) or interleukin (IL-1β)-promoted induction of nitric oxide synthase (NOS) in vascular smooth muscle, thereby inhibiting Arg-induced vascular relaxation[1].
Related Catalog
Target

IL-1β, NOS[1]

References

[1]. Moritoki H, et al. Inhibition by triptoquinone-A of LPS- and IL-1 beta-primed induction of NO synthase in rat thoracic aorta. Life Sci. 1996;59(3):PL49-54.  

 Chemical & Physical Properties

Density 1.21g/cm3
Boiling Point 489.6ºC at 760mmHg
Molecular Formula C20H24O4
Molecular Weight 328.40
Flash Point 264ºC
Exact Mass 328.16700
PSA 71.44000
LogP 3.62840
Vapour Pressure 6.3E-11mmHg at 25°C
Index of Refraction 1.572

 Safety Information

Hazard Codes Xi

 Synonyms

Tryptoquinone A
triptoquinone A