142950-86-5

142950-86-5 structure

Name: triptoquinonoic acid a
Chemical Name: (4aS,10aS)-1,4a-dimethyl-5,8-dioxo-7-propan-2-yl-4,9,10,10a-tetrahydro-3H-phenanthrene-2-carboxylic acid
CAS Number: 142950-86-5
Molecular Formula: C₂₀H₂₄O₄
Molecular Weight: 328.40
Catalog: Natural product Moss
Create Date: 2016-06-05 20:18:24
Modify Date: 2025-08-22 09:16:45
Triptoquinone A, an interleukin 1 inhibitor, inhibits endomycin (LPS) or interleukin (IL-1β)-promoted induction of nitric oxide synthase (NOS) in vascular smooth muscle, thereby inhibiting Arg-induced vascular relaxation[1].

Name	(4aS,10aS)-1,4a-dimethyl-5,8-dioxo-7-propan-2-yl-4,9,10,10a-tetrahydro-3H-phenanthrene-2-carboxylic acid
Synonyms	Tryptoquinone A triptoquinone A

Description	Triptoquinone A, an interleukin 1 inhibitor, inhibits endomycin (LPS) or interleukin (IL-1β)-promoted induction of nitric oxide synthase (NOS) in vascular smooth muscle, thereby inhibiting Arg-induced vascular relaxation[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Target	IL-1β, NOS[1]
References	[1]. Moritoki H, et al. Inhibition by triptoquinone-A of LPS- and IL-1 beta-primed induction of NO synthase in rat thoracic aorta. Life Sci. 1996;59(3):PL49-54.

Hazard Codes	Xi