PF-06459988
Modify Date: 2025-09-19 11:37:47
PF-06459988 structure
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Common Name | PF-06459988 | ||
|---|---|---|---|---|
| CAS Number | 1428774-45-1 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-06459988PF-06459988 is an irreversible inhibitor of T790M-Containing EGFR Mutants. |
| Name | PF-06459988 |
|---|---|
| Synonym | More Synonyms |
| Description | PF-06459988 is an irreversible inhibitor of T790M-Containing EGFR Mutants. |
|---|---|
| Related Catalog | |
| Target |
IC50: 45 nM (H1975 EGFR), 3.3 μM (EGFR) |
| References |
| InChIKey | ODMXWZROLKITMS-RISCZKNCSA-N |
|---|---|
| SMILES | C=CC(=O)N1CC(COc2nc(Nc3cnn(C)c3)nc3[nH]cc(Cl)c23)C(OC)C1 |
| Storage condition | 2-8℃ |
| RIDADR | NONH for all modes of transport |
|---|
| 1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one |