BChE-IN-20

Modify Date: 2024-02-02 13:06:25

BChE-IN-20 Structure
BChE-IN-20 structure
 Common Name BChE-IN-20
CAS Number 1428439-79-5 Molecular Weight 465.63
Density N/A Boiling Point N/A
Molecular Formula C27H39N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BChE-IN-20


BChE-IN-20 (compound 7c) is a highly potent BChE-selective inhibitor and exhibits IC50s of 105 and 2.3 nM for eqBChE and hBChE, respectively. BChE-IN-20 inhibits P glycoprotein with IC50 of 0.27 μM. BChE-IN-20 is a promising template to improve design and development of BChE-selective ligands of pharmaceutical interest, including inhibitors and fluorogenic probes.

 Names

Name BChE-IN-20

 BChE-IN-20 Biological Activity

Description BChE-IN-20 (compound 7c) is a highly potent BChE-selective inhibitor and exhibits IC50s of 105 and 2.3 nM for eqBChE and hBChE, respectively. BChE-IN-20 inhibits P glycoprotein with IC50 of 0.27 μM. BChE-IN-20 is a promising template to improve design and development of BChE-selective ligands of pharmaceutical interest, including inhibitors and fluorogenic probes.
Related Catalog
References

[1]. Modesto de Candia, et al. In-vitro and in-silico studies of annelated 1,4,7,8-tetrahydroazocine ester derivatives as nanomolar selective inhibitors of human butyrylcholinesterase. Chem Biol Interact. 2023 Oct 13:386:110741.  

 Chemical & Physical Properties

Molecular Formula C27H39N5O2
Molecular Weight 465.63
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Chemsrc provides BChE-IN-20(CAS#:1428439-79-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of BChE-IN-20 are included as well.>> amp version: BChE-IN-20

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