4-Chlorophenylguanidine hydrochloride

Modify Date: 2024-01-07 13:36:37

4-Chlorophenylguanidine hydrochloride Structure
4-Chlorophenylguanidine hydrochloride structure
Common Name 4-Chlorophenylguanidine hydrochloride
CAS Number 14279-91-5 Molecular Weight 206.07
Density N/A Boiling Point 333.9ºC at 760mmHg
Molecular Formula C7H9Cl2N3 Melting Point N/A
MSDS N/A Flash Point 155.7ºC

 Use of 4-Chlorophenylguanidine hydrochloride


4-Chlorophenylguanidine hydrochloride is a potent ASIC3 positive allosteric modulator and reverses the effects of ASIC3 desensitization. 4-Chlorophenylguanidine hydrochloride influences ASIC3 activity through directly activating the channel and increasing proton sensitivity. 4-Chlorophenylguanidine hydrochloride offers a chemical backbone for the design of new ASIC3 ligands to study ASIC3 in vivo[1].

 Names

Name 2-(4-chlorophenyl)guanidine,hydrochloride
Synonym More Synonyms

 4-Chlorophenylguanidine hydrochloride Biological Activity

Description 4-Chlorophenylguanidine hydrochloride is a potent ASIC3 positive allosteric modulator and reverses the effects of ASIC3 desensitization. 4-Chlorophenylguanidine hydrochloride influences ASIC3 activity through directly activating the channel and increasing proton sensitivity. 4-Chlorophenylguanidine hydrochloride offers a chemical backbone for the design of new ASIC3 ligands to study ASIC3 in vivo[1].
Related Catalog
References

[1]. Amruta S Agharkar, et al. 4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator. J Pharmacol Sci. 2017 Mar;133(3):184-186.  

 Chemical & Physical Properties

Boiling Point 333.9ºC at 760mmHg
Molecular Formula C7H9Cl2N3
Molecular Weight 206.07
Flash Point 155.7ºC
Exact Mass 205.01700
PSA 61.90000
LogP 3.32040
Vapour Pressure 0.000133mmHg at 25°C

 Safety Information

Hazard Codes Xi
HS Code 2925290090

 Customs

HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Synonyms

bw 65-100
4-chlorophenylguanidine hydrochloride
4-chlorophenylguanidine