(R)-Donepezil

Modify Date: 2025-08-28 12:52:13

Use of (R)-Donepezil

(R)-Donepezil is a R-enantiomer of Donepezil (HY-14566). Donepezil is a specific and potent AChE inhibitor[1][2].

Name	(R)-Donepezil

Description	(R)-Donepezil is a R-enantiomer of Donepezil (HY-14566). Donepezil is a specific and potent AChE inhibitor[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Lili W, et al. Steady-state plasma concentration of donepezil enantiomers and its stereoselective metabolism and transport in vitro. Chirality. 2013 Sep;25(9):498-505. [2]. Ogura, H., et al., Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol, 2000. 22(8): p. 609-13.

Description

(R)-Donepezil is a R-enantiomer of Donepezil (HY-14566). Donepezil is a specific and potent AChE inhibitor[1][2].

Related Catalog

Research Areas >> Cancer

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

References

Molecular Formula	C₂₄H₂₉NO₃
Molecular Weight	379.49
InChIKey	ADEBPBSSDYVVLD-HXUWFJFHSA-N
SMILES	COc1cc2c(cc1OC)C(=O)C(CC1CCN(Cc3ccccc3)CC1)C2