(R)-Donepezil

Names

[ CAS No. ]:
142698-19-9

[ Name ]:
(R)-Donepezil

Biological Activity

[Description]:

(R)-Donepezil is a R-enantiomer of Donepezil (HY-14566). Donepezil is a specific and potent AChE inhibitor[1][2].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Lili W, et al. Steady-state plasma concentration of donepezil enantiomers and its stereoselective metabolism and transport in vitro. Chirality. 2013 Sep;25(9):498-505.

[2]. Ogura, H., et al., Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol, 2000. 22(8): p. 609-13.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₉NO₃

[ Molecular Weight ]:
379.49

Related Compounds

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